GRAP2 antibody

Catalog No. ABIN2722223

Product Details anti-GRAP2 Antibody

Target: GRAP2 (GRB2-Related Adaptor Protein 2 (GRAP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GRAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Characteristics: Homo sapiens GRB2-related adaptor protein 2 (GRAP2)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human GRAP2(NP_004801) produced in HEK293T cell.

Clone: 1G2

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, IHC 1:150, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for GRAP2

Target: GRAP2 (GRB2-Related Adaptor Protein 2 (GRAP2))

Alternative Name: GRAP2 (GRAP2 Products)

Synonyms: GADS antibody, GRAP-2 antibody, GRB2L antibody, GRBLG antibody, GRID antibody, GRPL antibody, GrbX antibody, Grf40 antibody, Mona antibody, P38 antibody, Gads antibody, GrpL antibody, zgc:112091 antibody, GRAP2 antibody, grap2 antibody, zgc:65942 antibody, GRB2-related adaptor protein 2 antibody, GRB2-related adaptor protein 2a antibody, GRB2-related adaptor protein 2b antibody, GRAP2 antibody, Grap2 antibody, grap2a antibody, grap2 antibody, grap2b antibody

Background: This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.

Molecular Weight: 37.7 kDa

Gene ID: 9402

NCBI Accession: NM_004810

HGNC: 9402

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway