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HDAC6 antibody

HDAC6 Reactivity: Human, Monkey WB, IHC, FACS Host: Mouse Monoclonal 3E7 unconjugated
Catalog No. ABIN2722516
  • Target See all HDAC6 Antibodies
    HDAC6 (Histone Deacetylase 6 (HDAC6))
    Reactivity
    • 123
    • 41
    • 28
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Monkey
    Host
    • 110
    • 16
    • 1
    Mouse
    Clonality
    • 103
    • 24
    Monoclonal
    Conjugate
    • 72
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HDAC6 antibody is un-conjugated
    Application
    • 102
    • 43
    • 41
    • 27
    • 27
    • 26
    • 20
    • 15
    • 14
    • 9
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Characteristics
    Homo sapiens histone deacetylase 6 (HDAC6)
    Purification
    Purified from mouse ascites fluids by affinity chromatography
    Immunogen
    Full length human recombinant protein of human HDAC6 (NP_006035) produced in HEK293T cell.
    Clone
    3E7
    Isotype
    IgG1
    Top Product
    Discover our top product HDAC6 Primary Antibody
  • Application Notes
    WB 1:500~1000, IHC 1:150, FLOW 1:100
    Comment

    The concentration of the product may vary between diferrent lots.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5-1.0 mg/mL
    Buffer
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Wang, Hu, Tang, Xie: "HDAC6-mediated EGFR stabilization and activation restrict cell response to sorafenib in non-small cell lung cancer cells." in: Medical oncology (Northwood, London, England), Vol. 33, Issue 5, pp. 50, (2016) (PubMed).

  • Target
    HDAC6 (Histone Deacetylase 6 (HDAC6))
    Alternative Name
    HDAC6 (HDAC6 Products)
    Synonyms
    HD6 antibody, Hd6 antibody, Hdac5 antibody, Sfc6 antibody, mHDA2 antibody, CG6170 antibody, DHDAC2 antibody, DmHDAC2 antibody, Dmel\\CG6170 antibody, HDAC antibody, HDAC2 antibody, dHDAC2 antibody, dHDAC6 antibody, dmHDA404 antibody, hdac6 antibody, MGC53140 antibody, wu:fc31d02 antibody, dsim_GLEANR_17355 antibody, DsimGD17207 antibody, GD17207 antibody, HDAC6 antibody, ATHDA6 antibody, AXE1 antibody, HISTONE DEACETYLASE 6 antibody, MDC12.7 antibody, MDC12_7 antibody, RNA-MEDIATED TRANSCRIPTIONAL SILENCING 1 antibody, RPD3B antibody, RTS1 antibody, SIL1 antibody, histone deacetylase 6 antibody, histone deacetylase 6 antibody, Histone deacetylase 6 antibody, histone deacetylase 6 L homeolog antibody, GD17207 gene product from transcript GD17207-RB antibody, Histone DeAcetylase antibody, HDAC6 antibody, Hdac6 antibody, hdac6.L antibody, hdac6 antibody, Dsim\HDAC6 antibody, PTRG_03035 antibody, HDA6 antibody, hda-6 antibody
    Background
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.
    Molecular Weight
    131.2 kDa
    Gene ID
    10013
    NCBI Accession
    NM_006044
    HGNC
    10013
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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