PBX1 antibody

Catalog No. ABIN2728332

Product Details anti-PBX1 Antibody

Target: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PBX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Characteristics: Homo sapiens pre-B-cell leukemia homeobox 1 (PBX1), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human PBX1 (NP_002576) produced in HEK293T cell.

Clone: 1D9

Isotype: IgG1

Application Details

Application Notes: WB 1:2000, IF 1:100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PBX1

Target: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Alternative Name: PBX1 (PBX1 Products)

Synonyms: fi29e01 antibody, pbx1b antibody, wu:fi29e01 antibody, zgc:55265 antibody, 2310056B04Rik antibody, AI848790 antibody, AU015730 antibody, D230003C07Rik antibody, Pbx-1 antibody, Pbx1a antibody, Pbx1b antibody, PBX1A antibody, Xpbx1 antibody, Xpbx1b antibody, PBX homeobox 1 antibody, pre-B-cell leukemia homeobox 1a antibody, pre B cell leukemia homeobox 1 antibody, pre-B-cell leukemia homeobox 1 S homeolog antibody, PBX1 antibody, pbx1a antibody, Pbx1 antibody, pbx1.S antibody

Background: This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1,19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 46.4 kDa

Gene ID: 5087

NCBI Accession: NM_002585

HGNC: 5087