Retinoblastoma Protein (Rb) antibody

Catalog No. ABIN2743982

Product Details anti-Retinoblastoma Protein (Rb) Antibody

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoblastoma Protein (Rb) antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Specificity: Recognizes human retinoblastoma gene protein. Rb gene, a prototype of tumor suppressor genes has been associated with development and/or progression of bladder cancer as well as sarcoma and small cell lung cancer. Functional Rb gene loss has been reported to occur in bladder cancer and osteosarcoma. A significantly poorer tumor-free survival rate was noted for those patients who had a tumor with an altered Rb protein with or without vascular invasion.

Purification: Ig fraction

Immunogen: Recombinant human Rb protein.

Type of Immunogen: Recombinant protein

Clone: 1F8

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: IHC, IP (1:50), WB (1:50 - 1:100)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Buffer contains: 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for Retinoblastoma Protein (Rb)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Alternative Name: RB1 / Retinoblastoma / RB (Rb Protein Products)

Background: Name/Gene ID: RB1

Synonyms: RB1, p105-Rb, Osteosarcoma, PRb, Retinoblastoma, Retinoblastoma 1, OSRC, RB, Pp110

Gene ID: 5925

Pathways: Mitotic G1-G1/S Phases