Fission 1 antibody

Catalog No. ABIN2745530

Product Details anti-Fission 1 Antibody

Target: Fission 1 (FIS1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fission 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificity: Recognizes human, mouse and rat Fis1.

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Immunogen: Recombinant human Fis1.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: In PBS containing 10 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Expiry Date: 12 months

Target Details for Fission 1

Target: Fission 1 (FIS1)

Alternative Name: Fis1 (FIS1 Products)

Synonyms: TTC11 antibody, 2010003O14Rik antibody, Ttc11 antibody, fission, mitochondrial 1 antibody, FIS1 antibody, Fis1 antibody

Background: Fis1 promotes the fragmentation of the mitochondrial network and its perinuclear clustering. It can induce cytochrome c release from mitochondria to the cytosol, ultimately leading to apoptosis. It also mediates peroxisomal fission.

UniProt: Q9Y3D6

Pathways: Positive Regulation of Endopeptidase Activity