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IKBKG antibody (AA 40-210)
IKBKG
Reactivity: Human, Mouse
WB, ELISA, IP
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IKBKG Antibody
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Target
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IKBKG
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))
Binding Specificity
All epitopes for IKBKG antibodies
AA 40-210
Reactivity
All reactivities for IKBKG antibodies
Human, Mouse
Host
All hosts for IKBKG antibodies
Rabbit
Clonality
All clonalities for IKBKG antibodies
Polyclonal
Conjugate
All conjugates for IKBKG antibodies
This IKBKG antibody is un-conjugated
Application
All applications for IKBKG antibodies
Western Blotting (WB), ELISA, Immunoprecipitation (IP)
Specificity
Recognizes human and mouse IKK-gamma.
Cross-Reactivity
Human, Mouse (Murine)
Purification
Antigen affinity purified.
Immunogen
Recombinant human IKK-gamma (aa 40-210).
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
Lot specific
Buffer
In TRIS, pH 7.4, containing 50 % glycerol.
Storage
4 °C,-20 °C
Storage Comment
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date
12 months
Target Details for IKBKG
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Target
IKBKG
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))
Alternative Name
IKKgamma (IKBKG Products )
Synonyms
AMCBX1 antibody, FIP-3 antibody, FIP3 antibody, Fip3p antibody, IKK-gamma antibody, IP antibody, IP1 antibody, IP2 antibody, IPD2 antibody, NEMO antibody, ZC2HC9 antibody, 1110037D23Rik antibody, AI848108 antibody, AI851264 antibody, AW124339 antibody, IKK[g] antibody, Nemo antibody, nemo antibody, fj33c07 antibody, wu:fj33c07 antibody, zgc:113492 antibody, MGC97885 antibody, IKBKG antibody, IKBKG_1 antibody, IKBKG_2 antibody, CG16910 antibody, DmIKK-gamma antibody, DmIKKgamma antibody, Dmel\\CG16910 antibody, Dmikkgamma antibody, IKK antibody, IKK[[gamma]] antibody, IKKg antibody, IKKgamma antibody, KEY antibody, Kenny antibody, Key antibody, dIKK antibody, dIKK-gamma antibody, dmIKKgamma antibody, inhibitor of nuclear factor kappa B kinase subunit gamma antibody, inhibitor of kappaB kinase gamma antibody, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma antibody, inhibitor of nuclear factor kappa B kinase subunit gamma L homeolog antibody, kenny antibody, IKBKG antibody, Ikbkg antibody, ikbkg antibody, ikbkg.L antibody, IKBKG_1 antibody, key antibody
Background
IKK-gamma is the regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappaB, thus leading to the dissociation of the inhibitor/NF-kappaB complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. IKK-gamma is also considered to be a mediator for TAX activation of NF-kappaB and it could be implicated in NF-kappaB-mediated protection from cytokine toxicity. It is essential for viral activation of IRF3 and is involved in TLR3- and IFIH1-mediated antiviral innate response.
UniProt
Q9Y6K9
Pathways
NF-kappaB Signaling , RTK Signaling , TCR Signaling , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , M Phase , Production of Molecular Mediator of Immune Response , Hepatitis C , Protein targeting to Nucleus , Toll-Like Receptors Cascades , BCR Signaling , Ubiquitin Proteasome Pathway , S100 Proteins
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