Azurocidin antibody (AA 27-251)

Catalog No. ABIN2753372

Product Details anti-Azurocidin Antibody

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Binding Specificity: AA 27-251

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Azurocidin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity purified

Immunogen: Recombinant Human Azurocidin protein (27-251AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Azurocidin

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Alternative Name: AZU1 (AZU1 Products)

Synonyms: AZAMP antibody, AZU antibody, CAP37 antibody, HBP antibody, HUMAZUR antibody, NAZC antibody, AZU1 antibody, Azurocidin antibody, pHBP antibody, azurocidin 1 antibody, azurocidin antibody, AZU1 antibody, CpipJ_CPIJ007384 antibody

Background:

Background: This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria, this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G.

Aliases: Azu 1 antibody, AZU1 antibody, Azurocidin antibody, CAP37 antibody, CAP7_HUMAN antibody, Cationic antimicrobial protein 37 antibody, Cationic antimicrobial protein CAP37 antibody, HBP antibody, Heparin binding protein antibody, Heparin-binding protein antibody, HUMAZUR antibody, Neutrophil azurocidin antibody

UniProt: P20160