Cyclin D1 antibody (AA 1-233)

Catalog No. ABIN2753381

Product Details anti-Cyclin D1 Antibody

Target: Cyclin D1 (CCND1)

Binding Specificity: AA 1-233

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin D1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity purified

Immunogen: Recombinant Human B-cell lymphoma/leukemia 10 protein (1-233AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

References for anti-Cyclin D1 antibody (ABIN2753381)

Márquez-Jurado, Díaz-Colunga, das Neves, Martinez-Lorente, Almazán, Guantes, Iborra: "Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression." in: Nature communications, Vol. 9, Issue 1, pp. 389, (2018) (PubMed).

Target Details for Cyclin D1

Target: Cyclin D1 (CCND1)

Alternative Name: BCL1 (CCND1 Products)

Synonyms: BCL1 antibody, D11S287E antibody, PRAD1 antibody, U21B31 antibody, AI327039 antibody, CycD1 antibody, Cyl-1 antibody, bcl-1 antibody, cD1 antibody, cb161 antibody, cycd1 antibody, etID37810.7 antibody, fb52e01 antibody, fc45c08 antibody, fc83a12 antibody, id:ibd1198 antibody, wu:fb52e01 antibody, wu:fc45c08 antibody, wu:fc83a12 antibody, ccnd1b antibody, prad1 antibody, ccnd1 antibody, ccnd1a antibody, bcl1 antibody, d11s287e antibody, u21b31 antibody, CCND1 antibody, cyclin D1 antibody, cyclin D1 S homeolog antibody, cyclin D1 L homeolog antibody, CCND1 antibody, Ccnd1 antibody, ccnd1 antibody, ccnd1.S antibody, ccnd1.L antibody

Background:

Background: Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.

Aliases: AI132454 antibody, B cell CLL/lymphoma 10 antibody, B cell lymphoma/leukemia10 antibody, B-cell CLL/lymphoma 10 antibody, B-cell leukemia/lymphoma 10 antibody, B-cell lymphoma/leukemia 10 antibody, Bcl 10 antibody, Bcl-10 antibody, Bcl10 antibody, BCL10_HUMAN antibody, c E10 antibody, c-E10 antibody, C81403 antibody, CARD containing apoptotic signaling protein antibody, CARD containing molecule enhancing NF kappa B antibody, CARD containing molecule enhancing NF kB antibody, CARD containing molecule enhancing NF-kB antibody, CARD containing molecule enhancing NFkB antibody, CARD containing proapoptotic protein antibody, CARD like apoptotic protein antibody, CARD-containing apoptotic signaling protein antibody, CARD-containing molecule enhancing NF-kappa-B antibody, CARD-containing proapoptotic protein antibody, CARD-like apoptotic protein antibody, CARMEN antibody, Caspase recruiting domain containing protein antibody, caspase-recruiting domain-containing protein antibody, cCARMEN antibody, cE 10 antibody, cE10 antibody, CED 3/ICH 1 prodomain homologous E10 like regulator antibody, CED-3/ICH-1 prodomain homologous E10-like regulator antibody, CED3/ICH1 prodomain homologous E10 like regulator antibody, Cellular E10 antibody, Cellular homolog of vCARMEN antibody, Cellular-E10 antibody, CIPER antibody, CLAP antibody, hCLAP antibody, Mammalian CARD containing adapter molecule E10 antibody, Mammalian CARD-containing adapter molecule E10 antibody, mE 10 antibody, mE10 antibody, R-RCD1 antibody

UniProt: O95999

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling