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Orf1 (AA 60-240) antibody (Biotin)

Reactivity: Hepatitis E Virus (HEV) ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN2754621
  • Target
    Orf1
    Binding Specificity
    AA 60-240
    Reactivity
    • 5
    • 4
    • 1
    Hepatitis E Virus (HEV)
    Host
    • 10
    Rabbit
    Clonality
    • 10
    Polyclonal
    Conjugate
    • 3
    • 3
    • 2
    • 2
    Biotin
    Application
    • 8
    • 1
    ELISA
    Cross-Reactivity
    Hepatitis E Virus (HEV)
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 protein (60-240AA)
    Isotype
    IgG
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Orf1
    Target Type
    Viral Protein
    Background

    Background: Methyltransferase displays a cytoplasmic capping enzyme activity. This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus. The enzymatic reaction involves a covalent link between 7-methyl-GMP and the methyltransferase, whereas eukaryotic capping enzymes form a covalent complex only with GMP. Methyltransferase catalyzes transfer of a methyl group from S-adenosylmethionine to GTP and GDP to yield m7GTP or m7GDP. GMP, GpppG, and GpppA were poor substrates for the methyltransferase. This enzyme also displays guanylyltransferase activity to form a covalent complex, methyltransferase-m7GMP, from which 7-methyl-GMP is transferred to the mRNA to create the cap structure. Cap analogs such as m7GTP, m7GDP, et2m7GMP, and m2et7GMP inhibit the methyltransferase reaction (By similarity).

    Aliases: ORF1 antibody, Non-structural polyprotein pORF1 [Includes: Methyltransferase antibody, EC 2.1.1.- antibody, EC 2.7.7.-), Putative papain-like cysteine protease antibody, PLP antibody, EC 3.4.22.-), NTPase/helicase antibody, EC 3.6.4.-), RNA-directed RNA polymerase antibody, RdRp antibody, EC 2.7.7.48)] antibody

    UniProt
    P33424
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