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SLC12A2 antibody (C-Term)

SLC12A2 Reactivity: Human, Rat, Mouse, Cow, Dog, Pig, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2773831
  • Target See all SLC12A2 Antibodies
    SLC12A2 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2))
    Binding Specificity
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 33
    • 20
    • 18
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Cow, Dog, Pig, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)
    Host
    • 30
    • 4
    • 1
    • 1
    Rabbit
    Clonality
    • 32
    • 4
    Polyclonal
    Conjugate
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC12A2 antibody is un-conjugated
    Application
    • 19
    • 13
    • 9
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    IIAFEEIIEP YRLHEDDKEQ DIADKMKEDE PWRITDNELE LYKTKTYRQI
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
    Characteristics
    This is a rabbit polyclonal antibody against SLC12A2. It was validated on Western Blot.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human SLC12A2
    Top Product
    Discover our top product SLC12A2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1212 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Jansen, Peugh, Roden, Ojemann: "Impaired maturation of cortical GABA(A) receptor expression in pediatric epilepsy." in: Epilepsia, Vol. 51, Issue 8, pp. 1456-67, (2010) (PubMed).

    Chen, Sun, Deng, Hao, Chen, Xing, Jia, Ma, Wei, Zhu, Qian, Jiang, He: "Quantitative proteome analysis of HCC cell lines with different metastatic potentials by SILAC." in: Proteomics, Vol. 8, Issue 23-24, pp. 5108-18, (2008) (PubMed).

  • Target
    SLC12A2 (Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2))
    Alternative Name
    SLC12A2 (SLC12A2 Products)
    Synonyms
    BSC antibody, BSC2 antibody, NKCC1 antibody, Bsc2 antibody, Nkcc1 antibody, bsc2 antibody, 9330166H04Rik antibody, mBSC2 antibody, sy-ns antibody, solute carrier family 12 member 2 antibody, solute carrier family 12, member 2 antibody, SLC12A2 antibody, Slc12a2 antibody
    Background
    By moving chloride into epithelial cells, the Na-K-Cl cotransporter SLC12A2 aids transcellular movement of chloride across both secretory and absorptive epithelia.By moving chloride into epithelial cells, the Na-K-Cl cotransporter SLC12A2 aids transcellular movement of chloride across both secretory and absorptive epithelia (Payne et al., 1995). See also SLC12A1 (MIM 600839) and SLC12A3 (MIM 600968).[supplied by OMIM].
    Alias Symbols: BSC, BSC2, MGC104233, NKCC1
    Protein Interaction Partner: EGFR, MDM2, ATP4A, COMMD1, UBC, SEC13, STK39, OXSR1, SLC12A2, MAPK14,
    Protein Size: 1212
    Molecular Weight
    131 kDa
    Gene ID
    6558
    NCBI Accession
    NM_001046, NP_001037
    UniProt
    P55011
    Pathways
    Sensory Perception of Sound
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