MAFK antibody (N-Term)

Catalog No. ABIN2773900

Product Details anti-MAFK Antibody

Target: MAFK (Transcription Factor MafK (MAFK))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAFK antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TTNPKPNKAL KVKKEAGENA PVLSDDELVS MSVRELNQHL RGLTKEEVTR

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against Mafk. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 156 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAFK

Target: MAFK (Transcription Factor MafK (MAFK))

Alternative Name: Mafk (MAFK Products)

Synonyms: NFE2U antibody, P18 antibody, AW061068 antibody, NF-E2 antibody, Nfe2u antibody, MAF bZIP transcription factor K antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K antibody, Mafk antibody, MAFK antibody, mafk antibody

Background: Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.
Alias Symbols: AW061068, NF-E2, Nfe2u
Protein Interaction Partner: Bach2, Kmt2d, Ash2l, Nfe2, Nr4a3, Nfe2l2, Bach1,
Protein Size: 156

Molecular Weight: 17 kDa

Gene ID: 17135

NCBI Accession: NM_010757, NP_034887

UniProt: Q61827