SPINT2 antibody (Middle Region)

Catalog No. ABIN2773946

Product Details anti-SPINT2 Antibody

Target: SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))

Binding Specificity: Middle Region

Reactivity: Human, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPINT2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MLRCFRQQEN PPLPLGSKVV VLAGLFVMVL ILFLGASMVY LIRVARRNQE

Predicted Reactivity: Human: 100%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against SPINT2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SPINT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 252 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPINT2

Target: SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))

Alternative Name: SPINT2 (SPINT2 Products)

Synonyms: HAI-2 antibody, Pb antibody, DIAR3 antibody, HAI2 antibody, Kop antibody, PB antibody, AL024025 antibody, C76321 antibody, serine peptidase inhibitor, Kunitz type, 2 antibody, serine peptidase inhibitor, Kunitz type 2 antibody, serine protease inhibitor, Kunitz type 2 antibody, Spint2 antibody, SPINT2 antibody

Background: HAI-2 (SPINT2) is a candidate tumour suppressor gene that is frequently hypermethylated and underexpressed in human HCCs, and the KD-1 domain of HAI-2 is the key region responsible for its anti-invasive function. It is also implicated in human cervical cancer.
Alias Symbols: HAI-2, HAI2, Kop, PB, DIAR3
Protein Interaction Partner: TUBG1, APP, UBC, SUMO4, HGFAC, ITIH3, CTSB, ITIH2,
Protein Size: 252

Molecular Weight: 28 kDa

Gene ID: 10653

NCBI Accession: NM_021102, NP_066925

UniProt: O43291