Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

ACE2 antibody (Middle Region)

ACE2 Reactivity: Human, Mouse, Rat, Pig, Dog, Cow, Guinea Pig, Horse, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2774060
  • Target See all ACE2 Antibodies
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    Binding Specificity
    • 16
    • 16
    • 14
    • 10
    • 9
    • 9
    • 9
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Pig, Dog, Cow, Guinea Pig, Horse, Rabbit
    Host
    • 136
    • 20
    • 6
    Rabbit
    Clonality
    • 116
    • 46
    Polyclonal
    Conjugate
    • 79
    • 18
    • 12
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACE2 antibody is un-conjugated
    Application
    • 129
    • 76
    • 56
    • 36
    • 36
    • 19
    • 17
    • 11
    • 11
    • 10
    • 10
    • 6
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    FVTAPKNVSD IIPRTEVEKA IRMSRSRIND AFRLNDNSLE FLGIQPTLGP
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 86%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against ACE2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human ACE2
    Top Product
    Discover our top product ACE2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 805 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mak, Chin, Cunningham, Habib, Torresi, Sharland, Alexander, Angus, Herath: "ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 23, Issue 9, pp. 1434-43, (2015) (PubMed).

  • Target
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    Alternative Name
    ACE2 (ACE2 Products)
    Synonyms
    ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, ICH antibody, MVCD3 antibody, ACEH antibody, 2010305L05Rik antibody, zgc:92514 antibody, angiotensin I converting enzyme antibody, angiotensin I converting enzyme 2 antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antibody, ACE antibody, ACE2 antibody, Ace2 antibody, ace2 antibody
    Background
    ACE2 belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This protein catalyzes the cleavage of angiotensin I into angiotensin 1-9. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ACEH, DKFZP434A014
    Protein Interaction Partner: ACE2, AGT, CALM1, NTS, GHRL,
    Protein Size: 805
    Molecular Weight
    89 kDa
    Gene ID
    59272
    NCBI Accession
    NM_021804, NP_068576
    UniProt
    Q9BYF1
    Pathways
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
You are here:
Support