PTPN3 antibody (N-Term)

Catalog No. ABIN2774324

Product Details anti-PTPN3 Antibody

Target: PTPN3 (Protein tyrosine Phosphatase, Non-Receptor Type 3 (PTPN3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ASAGVAVYRK YICTSFYPWV NILKISFKRK KFFIHQRQKQ AESREHIVAF

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PTPN3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 782 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTPN3

Target: PTPN3 (Protein tyrosine Phosphatase, Non-Receptor Type 3 (PTPN3))

Alternative Name: PTPN3 (PTPN3 Products)

Synonyms: PTP-H1 antibody, PTPH1 antibody, 9530011I20Rik antibody, PTPCL antibody, protein tyrosine phosphatase, non-receptor type 3 antibody, PTPN3 antibody, Ptpn3 antibody

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DKFZp686N0569, PTPH1, PTP-H1
Protein Interaction Partner: NXT2, ZCCHC10, DIP2A, WDR6, LMO1, AKR1C1, YWHAQ, UBE3A, VDR, GHR, YWHAG, ADAM17, YWHAB, VCP, CD247, ZAP70, SFN,
Protein Size: 782

Molecular Weight: 86 kDa

Gene ID: 5774

NCBI Accession: NM_001145369, NP_001138841

UniProt: E9PGU7