SPSB1 antibody (Middle Region)
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- Target See all SPSB1 Antibodies
- SPSB1 (SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPSB1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RGLHVWQITW AMRQRGTHAV VGVATADAPL HSVGYTTLVG NNHESWGWDL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against SPSB1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human SPSB1
- Top Product
- Discover our top product SPSB1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 273 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SPSB1 (SplA/ryanodine Receptor Domain and SOCS Box Containing 1 (SPSB1))
- Alternative Name
- SPSB1 (SPSB1 Products)
- Synonyms
- SSB-1 antibody, SSB1 antibody, 1110014L01Rik antibody, 4930422J18Rik antibody, AI596360 antibody, AI854583 antibody, splA/ryanodine receptor domain and SOCS box containing 1 antibody, SPSB1 antibody, Spsb1 antibody
- Background
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SPSB1 is a probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Alias Symbols: SSB-1, SSB1
Protein Interaction Partner: PRMT6, KDM1A, SUV39H1, PRMT1, NOS2, HSP90AA1, ATM, TCEB2, TCEB1, RNF7, CUL5, Pawr, Ddx4, RASA1, MET, ELAVL1, UBC, TP73, TP53,
Protein Size: 273 - Molecular Weight
- 30 kDa
- Gene ID
- 80176
- NCBI Accession
- NM_025106, NP_079382
- UniProt
- Q96BD6
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