TLX1 antibody (Middle Region)

Catalog No. ABIN2774653

Product Details anti-TLX1 Antibody

Target: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Binding Specificity: Middle Region

Reactivity: Mouse, Human, Rat, Cow, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLX1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EAFQKSLAQP LPADPLCVHN SSLFALQNLQ PWSDDSTKIT SVTSVASACE

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TLX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TLX1

Application Details

Application Notes: WB Suggested Anti-TLX1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: Human heart.
Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 330 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TLX1

Target: TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))

Alternative Name: TLX1 (TLX1 Products)

Synonyms: Hox-11 antibody, Hox11 antibody, HOX11 antibody, TCL3 antibody, XHox11 antibody, XHox11L2 antibody, hox11 antibody, tlx1-a antibody, TLX-1 antibody, RGD1563655 antibody, SI:dZ46P4.1 antibody, Tlx-1 antibody, ztlx-1 antibody, T cell leukemia, homeobox 1 antibody, T-cell leukemia homeobox 1 antibody, T-cell leukemia homeobox 1 L homeolog antibody, T-cell leukemia, homeobox 1 antibody, Tlx1 antibody, TLX1 antibody, tlx1.L antibody, tlx1 antibody

Background: TLX1 contains 1 homeobox DNA-binding domain. TLX1 controls the genesis of the spleen. A chromosomal aberration involving TLX1, translocation t(10,14)(q24,q11) with TCRD, may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL).
Alias Symbols: HOX11, MGC163402, TCL3
Protein Interaction Partner: TLE1, PPP1CC, PPP1CB, NFIC, PPP2CA, PKNOX1, MEIS1, TLX1, PPP2CB,
Protein Size: 330

Molecular Weight: 34 kDa

Gene ID: 3195

NCBI Accession: NM_005521, NP_005512

UniProt: P31314