ABCB6 antibody (Middle Region)

Catalog No. ABIN2775320

Product Details anti-ABCB6 Antibody

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VTEWRTKFRR AMNTQENATR ARAVDSLLNF ETVKYYNAES YEVERYREAI

Predicted Reactivity: Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ABCB6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ABCB6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 842 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ABCB6

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Alternative Name: ABCB6 (ABCB6 Products)

Synonyms: ABCB6 antibody, abcb6 antibody, ABC antibody, ABC14 antibody, LAN antibody, MCOPCB7 antibody, MTABC3 antibody, PRP antibody, umat antibody, 1200005B17Rik antibody, ATP binding cassette subfamily B member 6 (Langereis blood group) antibody, ATP binding cassette subfamily B member 6 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 6a antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 6 antibody, ABCB6 antibody, abcb6a antibody, abcb6 antibody, Abcb6 antibody

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
Alias Symbols: ABC, ABC14, EST45597, FLJ22414, MTABC3, PRP, umat, MCOPCB7
Protein Interaction Partner: UBC, RNF2, BMI1, TOMM40, TOLLIP, PIK3R3,
Protein Size: 842

Molecular Weight: 94 kDa

Gene ID: 10058

NCBI Accession: NM_005689, NP_005680

UniProt: Q9NP58

Pathways: Transition Metal Ion Homeostasis