EBI3 antibody (Middle Region)

Catalog No. ABIN2775323

Product Details anti-EBI3 Antibody

Target: EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))

Binding Specificity: Middle Region

Reactivity: Human, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EBI3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TAVHPWGSSS SFVPFITEHI IKPDPPEGVR LSPLAERQLQ VQWEPPGSWP

Predicted Reactivity: Dog: 91%, Guinea Pig: 93%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against EBI3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EBI3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 229 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EBI3

Target: EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))

Alternative Name: EBI3 (IL-27b Products)

Synonyms: IL-27B antibody, IL27B antibody, EBI3 antibody, il-27rb antibody, si:dkey-97a13.4 antibody, EBI-3 antibody, IL-27 antibody, Epstein-Barr virus induced 3 antibody, Epstein-Barr virus induced gene 3 antibody, EBI3 antibody, ebi3 antibody, Ebi3 antibody

Target Type: Viral Protein

Background: This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
Alias Symbols: IL27B, IL-27B
Protein Interaction Partner: SMAD3, IL27RA, MDFI, GOSR1, IL12A, CANX,
Protein Size: 229

Molecular Weight: 23 kDa

Gene ID: 10148

NCBI Accession: NM_005755, NP_005746

UniProt: Q14213