CACNB3 antibody (C-Term)

Catalog No. ABIN2776096

Product Details anti-CACNB3 Antibody

Target: CACNB3 (Calcium Channel, Voltage-Dependent, beta 3 Subunit (CACNB3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNB3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EHSPLERDSL MPSDEASESS RQAWTGSSQR SSRHLEEDYA DAYQDLYQPH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CACNB3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CACNB3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 484 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CACNB3

Target: CACNB3 (Calcium Channel, Voltage-Dependent, beta 3 Subunit (CACNB3))

Alternative Name: CACNB3 (CACNB3 Products)

Synonyms: vgcc antibody, xo28 antibody, xo32 antibody, o32-a antibody, cacnlb3 antibody, VGCC antibody, CACNB3 antibody, CAB3 antibody, CACNLB3 antibody, Beta3 antibody, Cchb3 antibody, CACH3B antibody, cacnb3 antibody, Cacnb3 antibody, calcium channel, voltage-dependent, beta 3 subunit S homeolog antibody, calcium channel, voltage-dependent, beta 3 subunit L homeolog antibody, calcium voltage-gated channel auxiliary subunit beta 3 antibody, calcium channel, voltage-dependent, beta 3b antibody, calcium channel, voltage-dependent, beta 3 subunit antibody, calcium channel, voltage-dependent, beta 3a antibody, cacnb3.S antibody, cacnb3.L antibody, CACNB3 antibody, cacnb3b antibody, cacnb3 antibody, Cacnb3 antibody, cacnb3a antibody

Background: The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Alias Symbols: CAB3, CACNLB3
Protein Interaction Partner: FASLG, CACNA1C,
Protein Size: 484

Molecular Weight: 53 kDa

Gene ID: 784

NCBI Accession: NM_000725, NP_000716

UniProt: P54284

Pathways: Myometrial Relaxation and Contraction