×
For best experience we recommend to activate Javascript in your browser.
SCN7A antibody (N-Term)
SCN7A
Reactivity: Human, Rat, Mouse, Dog, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SCN7A Antibody
(hide)
Target
See all SCN7A Antibodies
SCN7A
(Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A))
Binding Specificity
All epitopes for SCN7A antibodies
N-Term
Reactivity
Human, Rat, Mouse, Dog, Guinea Pig
Host
All hosts for SCN7A antibodies
Rabbit
Clonality
All clonalities for SCN7A antibodies
Polyclonal
Conjugate
All conjugates for SCN7A antibodies
This SCN7A antibody is un-conjugated
Application
All applications for SCN7A antibodies
Western Blotting (WB)
Sequence
PFIYGNLSQG MVSEPLEDVD PYYYKKKNTF IVLNKNRTIF RFNAASILCT
Predicted Reactivity
Dog: 79%, Guinea Pig: 80%, Human: 100%, Mouse: 79%, Rat: 79%
Characteristics
This is a rabbit polyclonal antibody against SCN7A. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of human SCN7A
Top Product
Discover our top product SCN7A Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for SCN7A
(hide)
Target
SCN7A
(Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A))
Alternative Name
SCN7A (SCN7A Products )
Synonyms
1110034K09Rik antibody, AI642000 antibody, NaG antibody, Nav2 antibody, Nav2.3 antibody, Nax antibody, Scn6a antibody, Na-G antibody, Nav2.1 antibody, Nav2.2 antibody, SCN6A antibody, sodium channel, voltage-gated, type VII, alpha antibody, sodium voltage-gated channel alpha subunit 7 antibody, Scn7a antibody, SCN7A antibody
Background
This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics, the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels, domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. Alias Symbols: NaG, SCN6A, Nav2.1, Nav2.2 Protein Size: 762
Molecular Weight
83 kDa
Gene ID
6332
NCBI Accession
NM_002976 , NP_002967
UniProt
Q01118
Recently viewed
(hide)