KCNAB3 antibody (N-Term)

Catalog No. ABIN2776166

Product Details anti-KCNAB3 Antibody

Target: KCNAB3 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 3 (KCNAB3))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNAB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RNLGKSGLRV SCLGLGTWVT FGSQISDETA EDVLTVAYEH GVNLFDTAEV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KCNAB3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNAB3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 404 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNAB3

Target: KCNAB3 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 3 (KCNAB3))

Alternative Name: KCNAB3 (KCNAB3 Products)

Synonyms: KCNAB3 antibody, AKR6A9 antibody, KCNA3.1B antibody, KCNA3B antibody, KV-BETA-3 antibody, C330022D06Rik antibody, Kcnab4 antibody, mKv(beta)4 antibody, akr6a9 antibody, kcna3.1b antibody, kcna3b antibody, kcnb4-A antibody, kv-beta-3 antibody, kvb-b antibody, kvb4 antibody, xKvbeta4 antibody, potassium voltage-gated channel subfamily A regulatory beta subunit 3 antibody, potassium voltage-gated channel, shaker-related subfamily, beta member 3 antibody, potassium channel, voltage gated subfamily A regulatory beta subunit 3 L homeolog antibody, KCNAB3 antibody, Kcnab3 antibody, kcnab3.L antibody

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member and the KCNA5 gene product assemble into a heteromultimeric A-type channel that inactivates completely and is significantly faster than other A-type Kv channels.
Alias Symbols: AKR6A9, KCNA3B, KCNA3.1B, KV-BETA-3
Protein Interaction Partner: APP, UBC, NEDD4L,
Protein Size: 404

Molecular Weight: 44 kDa

Gene ID: 9196

NCBI Accession: NM_004732, NP_004723

UniProt: O43448