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KCNJ4 antibody (Middle Region)

KCNJ4 Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776173
  • Target See all KCNJ4 Antibodies
    KCNJ4 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4))
    Binding Specificity
    • 15
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 32
    • 14
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Dog, Guinea Pig
    Host
    • 32
    • 1
    Rabbit
    Clonality
    • 32
    • 1
    Polyclonal
    Conjugate
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNJ4 antibody is un-conjugated
    Application
    • 26
    • 18
    • 7
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    AVAAGLGLEA GSKEEAGIIR MLEFGSHLDL ERMQASLPLD NISYRRESAI
    Predicted Reactivity
    Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against KCNJ4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human KCNJ4
    Top Product
    Discover our top product KCNJ4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 445 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KCNJ4 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4))
    Alternative Name
    KCNJ4 (KCNJ4 Products)
    Synonyms
    KCNJ4 antibody, CKIR2.3 antibody, HIR antibody, HIRK2 antibody, HRK1 antibody, IRK-3 antibody, IRK3 antibody, Kir2.3 antibody, Kcnf2 antibody, MB-IRK3 antibody, Hirk2 antibody, potassium voltage-gated channel subfamily J member 4 antibody, potassium inwardly-rectifying channel, subfamily J, member 4 antibody, KCNJ4 antibody, Kcnj4 antibody
    Background
    KCNJ4 is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have??een found for this gene. Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neuronsSeveral different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.
    Alias Symbols: HIR, HIRK2, HRK1, IRK3, Kir2.3, MGC142066, MGC142068, IRK-3
    Protein Interaction Partner: SNTA1, LIN7B, GNGT2, DLG2, IL16, DLG4, DLG1, KCNJ2, CASK, PRKCD, LIN7C, LIN7A, DMD,
    Protein Size: 445
    Molecular Weight
    49 kDa
    Gene ID
    3761
    NCBI Accession
    NM_004981, NP_004972
    UniProt
    P48050
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