TRPC7 antibody (C-Term)

Catalog No. ABIN2776232

Product Details anti-TRPC7 Antibody

Target: TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPC7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KAQVDRENDE VNEGELKEIK QDISSLRYEL LEEKSQATGE LADLIQQLSE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TRPC7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TRPC7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRPC7

Target: TRPC7 (Transient Receptor Potential Cation Channel, Subfamily C, Member 7 (TRPC7))

Alternative Name: TRPC7 (TRPC7 Products)

Synonyms: TRP7 antibody, TRP-7 antibody, Trrp8 antibody, TRPC7 antibody, TRPM2 antibody, transient receptor potential cation channel subfamily C member 7 antibody, transient receptor potential cation channel, subfamily C, member 7 antibody, short transient receptor potential channel 7 antibody, TRPC7 antibody, Trpc7 antibody, LOC100012798 antibody

Background: TRPC7 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC7 probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It is activated by diacylglycerol (DAG) and may also be activated by intracellular calcium store depletion.
Alias Symbols: TRP7
Protein Interaction Partner: MX1, ITPR3, TRPC7, TRPC6, TRPC3,
Protein Size: 862

Molecular Weight: 99 kDa

Gene ID: 57113

NCBI Accession: NM_020389, NP_065122

UniProt: Q9HCX4