HTR3C antibody (Middle Region)
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- Target See all HTR3C products
- HTR3C (5-Hydroxytryptamine (serotonin) Receptor 3, Family Member C (HTR3C))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HTR3C antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- CCPTAPQKGN KGLGLTLTHL PGPKEPGELA GKKLGPRETE PDGGSGWTKT
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against HTR3C. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human HTR3C
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 447 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HTR3C (5-Hydroxytryptamine (serotonin) Receptor 3, Family Member C (HTR3C))
- Alternative Name
- HTR3C (HTR3C Products)
- Synonyms
- 5-hydroxytryptamine receptor 3C antibody, 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic antibody, HTR3C antibody, LOC100066962 antibody, LOC607416 antibody, LOC706232 antibody
- Background
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HTR3C is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3.
Alias Symbols: -
Protein Size: 447 - Molecular Weight
- 50 kDa
- Gene ID
- 170572
- NCBI Accession
- NM_130770, NP_570126
- UniProt
- Q8WXA8
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