KCNK10 antibody (N-Term)

Catalog No. ABIN2776274

Product Details anti-KCNK10 Antibody

Target: KCNK10 (Potassium Channel, Subfamily K, Member 10 (KCNK10))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK10 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EKAEFLRDHV CVSPQELETL IQHALDADNA GVSPIGNSSN NSSHWDLGSA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KCNK10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNK10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 538 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNK10

Target: KCNK10 (Potassium Channel, Subfamily K, Member 10 (KCNK10))

Alternative Name: KCNK10 (KCNK10 Products)

Synonyms: KCNK10 antibody, K2p10.1 antibody, TREK-2 antibody, TREK2 antibody, 1700024D23Rik antibody, 3010005K24Rik antibody, Trek2 antibody, k2p10.1 antibody, trek-2 antibody, trek2 antibody, potassium two pore domain channel subfamily K member 10 antibody, potassium channel, subfamily K, member 10 antibody, potassium channel, two pore domain subfamily K, member 10 L homeolog antibody, KCNK10 antibody, Kcnk10 antibody, kcnk10.L antibody

Background: KCNK10 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Three transcript variants have been identified for this gene. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Three transcript variants have been identified for this gene.
Alias Symbols: K2p10.1, TREK-2, TREK2
Protein Interaction Partner: PPP1CA, UBC,
Protein Size: 538

Molecular Weight: 60 kDa

Gene ID: 54207

NCBI Accession: NM_021161, NP_066984

UniProt: P57789