P2RX2 antibody (N-Term)

Catalog No. ABIN2776293

Product Details anti-P2RX2 Antibody

Target: P2RX2 (Purinergic Receptor P2X, Ligand Gated Ion Channel 2 (P2RX2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Rabbit, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DGASVSQFLG TMAPNFTILI KNSIHYPKFH FSKGNIADRT DGYLKRCTFH

Predicted Reactivity: Cow: 75%, Guinea Pig: 83%, Human: 100%, Rabbit: 79%, Rat: 90%

Characteristics: This is a rabbit polyclonal antibody against P2RX2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human P2RX2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 399 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-P2RX2 antibody (ABIN2776293)

Chen, Ho, Ho, Ho, Lee, Yu, Sit: "Gaseous and particulate polycyclic aromatic hydrocarbons (PAHs) emissions from commercial restaurants in Hong Kong." in: Journal of environmental monitoring : JEM, Vol. 9, Issue 12, pp. 1402-9, (2007) (PubMed).

Target Details for P2RX2

Target: P2RX2 (Purinergic Receptor P2X, Ligand Gated Ion Channel 2 (P2RX2))

Alternative Name: P2RX2 (P2RX2 Products)

Synonyms: DFNA41 antibody, P2X2 antibody, P2X2a antibody, P2x2 antibody, p2xr2 antibody, P2RX2 antibody, purinergic receptor P2X 2 antibody, purinergic receptor P2X, ligand-gated ion channel, 2 antibody, P2RX2 antibody, P2rx2 antibody, p2rx2 antibody

Background: P2RX2 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for P2RX2 The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene.
Alias Symbols: MGC129601, P2X2
Protein Interaction Partner: P2RX2, GABRR1, P2RX3, P2RX1,
Protein Size: 399

Molecular Weight: 44 kDa

Gene ID: 22953

NCBI Accession: NM_012226, NP_036358

Pathways: Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity