ABCB4 antibody (Middle Region)

Catalog No. ABIN2776967

Product Details anti-ABCB4 Antibody

Target: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GRTCIVIAHR LSTIQNADLI VVFQNGRVKE HGTHQQLLAQ KGIYFSMVSV

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 92%, Rabbit: 86%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against ABCB4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ABCB4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1279 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ABCB4

Target: ABCB4 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 4 (ABCB4))

Alternative Name: ABCB4 (ABCB4 Products)

Synonyms: ABC21 antibody, GBD1 antibody, ICP3 antibody, MDR2 antibody, MDR2/3 antibody, MDR3 antibody, PFIC-3 antibody, PGY3 antibody, zgc:172149 antibody, Mdr2 antibody, Pgy-2 antibody, Pgy2 antibody, mdr-2 antibody, Pgy3 antibody, ABCB4a antibody, DEFB1 antibody, PGP2 antibody, PGY2 antibody, PGP3 antibody, ABCB4 antibody, RUNDC3B antibody, ATP binding cassette subfamily B member 4 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 4 antibody, beta-defensin 1-like antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 1B antibody, RUN domain-containing protein 3B antibody, ABCB4 antibody, abcb4 antibody, Abcb4 antibody, LOC100861170 antibody, Abcb1b antibody, LOC101122517 antibody

Background: ABCB4, a membrane-associated protein, is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. This protein is a member of the MDR/TAP subfamily. Member
Alias Symbols: ABC21, GBD1, MDR2, MDR2/3, MDR3, PFIC-3, PGY3
Protein Interaction Partner: PIGY, TESK1, HAX1,
Protein Size: 1279

Molecular Weight: 141 kDa

Gene ID: 5244

NCBI Accession: NM_000443, NP_000434

UniProt: P21439

Pathways: Regulation of Lipid Metabolism by PPARalpha