CYP2A13 antibody (C-Term)

Catalog No. ABIN2777000

Product Details anti-CYP2A13 Antibody

Target: CYP2A13 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 13 (CYP2A13))

Binding Specificity: C-Term

Reactivity: Human, Rat, Cow, Guinea Pig, Horse, Mouse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2A13 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DPRFFSNPRD FNPQHFLDKK GQFKKSDAFV PFSIGKRYCF GEGLARMELF

Predicted Reactivity: Cow: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Rat: 91%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against CYP2A13. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CYP2A13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 494 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CYP2A13

Target: CYP2A13 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 13 (CYP2A13))

Alternative Name: CYP2A13 (CYP2A13 Products)

Synonyms: CPAD antibody, CYP2A antibody, CYPIIA13 antibody, MGC86391 antibody, MGC88881 antibody, CYP2A13 antibody, CYP2A6 antibody, cytochrome P450 family 2 subfamily A member 13 antibody, cytochrome P450, family 2, subfamily A, polypeptide 13 antibody, cytochrome P450 family 2 subfamily A member 13 L homeolog antibody, cytochrome P450 family 2 subfamily A polypeptide 13 antibody, cytochrome P450 2A13 antibody, CYP2A13 antibody, cyp2a13.L antibody, cyp2a13 antibody, LOC540707 antibody

Background: CYP2A13 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
Alias Symbols: CPAD, CYP2A, CYPIIA13
Protein Size: 494

Molecular Weight: 54 kDa

Gene ID: 1553

NCBI Accession: NM_000766, NP_000757

UniProt: Q16696