DBP antibody (Middle Region)

Catalog No. ABIN2777367

The Rabbit Polyclonal anti-DBP antibody has been validated for WB and IHC. It is suitable to detect DBP in samples from Human, Rat, Mouse, Dog, Cow, Horse, Sheep and Pig. There are 2+ publications available.

Quick Overview for DBP antibody (Middle Region) (ABIN2777367)

Target: DBP (D Site of Albumin Promoter (Albumin D-Box) Binding Protein (DBP))

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Sheep, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DBP Antibody

Binding Specificity: Middle Region

Sequence: SSPGHAPARA ALGTASGHRA GLTSRDTPSP VDPDTVEVLM TFEPDPADLA

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against DBP. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DBP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 325 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DBP antibody (ABIN2777367)

Ohta, Taguchi, Matsumura, Nakabayashi, Akiyama, Yamamoto, Fujimoto, Suetomi, Yanai, Shinoda, Tanizawa: "Clock Gene Dysregulation Induced by Chronic ER Stress Disrupts β-cell Function." in: EBioMedicine, Vol. 18, pp. 146-156, (2017) (PubMed).

Hamamura, Matsunaga, Ikeda, Kondo, Ikeyama, Tokushige, Itcho, Furuichi, Yoshida, Matsuda, Yasuda, Doi, Yokota, Amamoto, Aramaki, Irino, Koyanagi, Ohdo: "Alterations of Hepatic Metabolism in Chronic Kidney Disease via D-box-binding Protein Aggravate the Renal Dysfunction." in: The Journal of biological chemistry, Vol. 291, Issue 10, pp. 4913-27, (2016) (PubMed).

Target Details for DBP

Target: DBP (D Site of Albumin Promoter (Albumin D-Box) Binding Protein (DBP))

Alternative Name: DBP

Background: DBP is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family (Khatib et al., 1994.
Alias Symbols: DABP
Protein Interaction Partner: BATF2, BATF3, BATF, EPAS1, DDIT3, CEBPG, CEBPA, ATF3, HLF, EP300, TEF,
Protein Size: 325

Molecular Weight: 34 kDa

Gene ID: 1628

NCBI Accession: NM_001352, NP_001343

UniProt: Q10586