RBAK antibody (Middle Region)

Catalog No. ABIN2777686

Product Details anti-RBAK Antibody

Target: RBAK (RB-Associated KRAB Zinc Finger (RBAK))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Guinea Pig, Horse, Rat, Cow, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBAK antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HYRSHLEEKP YECNECGKTF NLNSAFIRHR KVHTEEKSHE CSECGKFSQL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RBAK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RBAK

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 714 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RBAK

Target: RBAK (RB-Associated KRAB Zinc Finger (RBAK))

Alternative Name: RBAK (RBAK Products)

Synonyms: ZNF769 antibody, RGD1562875 antibody, RB associated KRAB zinc finger antibody, RB-associated KRAB zinc finger antibody, RB-associated KRAB repressor antibody, RB-associated KRAB zinc finger protein antibody, RBAK antibody, Rbak antibody, LOC100037682 antibody, LOC100343106 antibody

Background: RBAK is a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif.
Alias Symbols: ZNF769
Protein Interaction Partner: SUMO1, RB1, SMARCAD1, Trim28, AR,
Protein Size: 714

Molecular Weight: 83 kDa

Gene ID: 57786

NCBI Accession: NM_021163, NP_066986

UniProt: Q9NYW8