RFX4 antibody (N-Term)

Catalog No. ABIN2777812

Product Details anti-RFX4 Antibody

Target: RFX4 (Regulatory Factor X 4 (RFX4))

Binding Specificity: N-Term

Reactivity: Rat, Human, Mouse, Dog, Horse, Rabbit, Cow, Guinea Pig, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RFX4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SETGKKEVSK QTVAYSPRSK LGTLLPEFPN VKDLNLPASL PEEKVSTFIM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RFX4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RFX4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RFX4

Target: RFX4 (Regulatory Factor X 4 (RFX4))

Alternative Name: RFX4 (RFX4 Products)

Synonyms: NYD-SP10 antibody, 4933412G19Rik antibody, NYD-sp10 antibody, RGD1562092 antibody, regulatory factor X, 4 antibody, regulatory factor X4 antibody, regulatory factor X, 4 (influences HLA class II expression) antibody, rfx4 antibody, RFX4 antibody, Rfx4 antibody

Background: RFX4 is a transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX4 is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. RFX4 may be a transcriptional repressor rather than a transcriptional activator.This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: NYD-SP10
Protein Interaction Partner: RFX3, RFX2, ESR1, RFX4,
Protein Size: 563

Molecular Weight: 61 kDa

Gene ID: 5992

NCBI Accession: NM_213594, NP_998759