SMARCD2 antibody (Middle Region)

Catalog No. ABIN2777855

Product Details anti-SMARCD2 Antibody

Target: SMARCD2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 2 (SMARCD2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMARCD2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QEIASLDVKI HETIESINQL KTQRDFMLSF STDPQDFIQE WLRSQRRDLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against SMARCD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SMARCD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 531 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SMARCD2

Target: SMARCD2 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 2 (SMARCD2))

Alternative Name: SMARCD2 (SMARCD2 Products)

Synonyms: SMARCD2 antibody, rsc6p antibody, baf60b antibody, cracd2 antibody, pro2451 antibody, BAF60B antibody, CRACD2 antibody, Rsc6p antibody, AW322457 antibody, Baf60b antibody, BAF60b antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 L homeolog antibody, SMARCD2 antibody, smarcd2 antibody, smarcd2.L antibody, Smarcd2 antibody

Background: SMARCD2 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein.The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: BAF60B, CRACD2, PRO2451, Rsc6p
Protein Interaction Partner: NOTCH2NL, UBC, RNF2, BMI1, RBBP5, NUDCD2, SIRT1, BAZ1B, KYNU, ARID1A, TOP2B, SMARCE1, SMARCD1, SMARCC2, SMARCC1, SMARCB1, SMARCA4, SMARCA2, BPTF, CUL3, SMARCAD1, Bcl7b, UNKL, TP63, TP73, TP53, XRN1, BRCA1,
Protein Size: 531

Molecular Weight: 59 kDa

Gene ID: 6603

NCBI Accession: NM_001098426, NP_001091896

UniProt: B4DV56