NR2E1 antibody (Middle Region)

Catalog No. ABIN2777931

Product Details anti-NR2E1 Antibody

Target: NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR2E1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RTSTIRKQVA LYFRGHKEEN GAAAHFPSAA LPAPAFFTAV TQLEPHGLEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against NR2E1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NR2E1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 385 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NR2E1

Target: NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))

Alternative Name: NR2E1 (NR2E1 Products)

Background: The NR2E1 gene is a member of the steroid nuclear receptor superfamily and is predominately expressed in the brain. The contributions of this gene to human B-cell leukemia and to brain development are unknown at present.
Alias Symbols: TLL, TLX, XTLL
Protein Interaction Partner: NSD1, BCL11A, UBC, ERBB2IP, SP1, HDAC7, HDAC5, HDAC3, GSE1, RCOR1, KDM1A, ZMYM2, HDAC2, HDAC1, Gug, ATN1, RERE,
Protein Size: 385

Molecular Weight: 42 kDa

Gene ID: 7101

NCBI Accession: NM_003269, NP_003260

UniProt: Q9Y466

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance