TFAP2B antibody (C-Term)

Catalog No. ABIN2777940

This anti-TFAP2B antibody is a Rabbit Polyclonal antibody detecting TFAP2B in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig and Sheep.

Quick Overview for TFAP2B antibody (C-Term) (ABIN2777940)

Target: TFAP2B (Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFAP2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TFAP2B Antibody

Binding Specificity: C-Term

Sequence: AQDRTPIGNS RPSPILEPGI QSCLTHFSLI THGFGAPAIC AALTALQNYL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 79%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against TFAP2B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TFAP2B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 449 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFAP2B

Target: TFAP2B (Transcription Factor AP-2 beta (Activating Enhancer Binding Protein 2 Beta) (TFAP2B))

Alternative Name: TFAP2B

Background: TFAP2B belongs to the AP-2 family which is developmentally regulated and have distinct overlapping functions in the regulation of many genes governing growth and differentiation. TFAP2B binds DNA as a dimmer and can form homodimers or heterodimers with other AP-2 family members. It may be a candidate for conferring susceptibility to type 2 didabetes.
Alias Symbols: AP-2B, AP2-B
Protein Interaction Partner: YEATS4, UBC, KCTD1, UBE2I, SUMO1, SSBP4, LZTR1, VPS11, HIST1H2AC, CITED4, MYC, CITED2, CITED1,
Protein Size: 449

Molecular Weight: 49 kDa

Gene ID: 7021

NCBI Accession: NM_003221, NP_003212

UniProt: Q92481

Pathways: Carbohydrate Homeostasis, Synaptic Membrane