NR1D2 antibody (Middle Region)

Catalog No. ABIN2778065

Product Details anti-NR1D2 Antibody

Target: NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Rabbit, Cow, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR1D2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSLFTAVVLV SADRSGIENV NSVEALQETL IRALRTLIMK NHPNEASIFT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against NR1D2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NR1D2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 579 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NR1D2

Target: NR1D2 (Nuclear Receptor Subfamily 1, Group D, Member 2 (NR1D2))

Alternative Name: NR1D2 (NR1D2 Products)

Synonyms: BD73 antibody, EAR-1R antibody, RVR antibody, HZF-2 antibody, Rev-erb antibody, REV-ERBB antibody, NR1D2 antibody, rvr antibody, bd73 antibody, hzf2 antibody, ear-1r antibody, hs.37288 antibody, NR1D2-A antibody, Reverbbeta-A antibody, reverbb1 antibody, reverbb antibody, reverbb2 antibody, zgc:92019 antibody, nuclear receptor subfamily 1 group D member 2 antibody, nuclear receptor subfamily 1, group D, member 2 antibody, nuclear receptor subfamily 1, group D, member 2a antibody, nuclear receptor subfamily 1, group D, member 2b antibody, NR1D2 antibody, Nr1d2 antibody, nr1d2 antibody, nr1d2a antibody, nr1d2b antibody

Background: NR1D2 is a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. NR1D2 functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
Alias Symbols: BD73, EAR-1r, HZF2, Hs.37288, RVR, EAR-1R
Protein Interaction Partner: MID2, RBPMS, TRIM27, NOTCH2NL, KRTAP10-9, KRT40, KRTAP4-2, PRMT6, SKP1, UBC, SIN3B, KAT5, NCOR1, TAF9, TAF6, HDAC1, GTF2B, NCOA5, UBE2I, CUL1, NR1D1, RGN,
Protein Size: 579

Molecular Weight: 65 kDa

Gene ID: 9975

NCBI Accession: NM_005126, NP_005117

UniProt: Q14995

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway