Asialoglycoprotein Receptor 2 antibody (N-Term)

Catalog No. ABIN2778142

Product Details anti-Asialoglycoprotein Receptor 2 Antibody

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Binding Specificity: N-Term

Reactivity: Human, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Asialoglycoprotein Receptor 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: STLTEVQAIS THGGSVGDKI TSLGAKLEKQ QQDLKADHDA LLFHLKHFPV

Predicted Reactivity: Human: 100%, Pig: 77%

Characteristics: This is a rabbit polyclonal antibody against ASGR2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ASGR2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 311 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Asialoglycoprotein Receptor 2

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Alternative Name: ASGR2 (ASGR2 Products)

Synonyms: ASGR2 antibody, asgr2 antibody, MGC137129 antibody, ASGP-R2 antibody, ASGPR2 antibody, CLEC4H2 antibody, HBXBP antibody, HL-2 antibody, Asgr antibody, Asgr-2 antibody, asialoglycoprotein receptor 2 antibody, C-type lectin domain family 10 member A antibody, ASGR2 antibody, clec10a antibody, Asgr2 antibody, LOC100347178 antibody

Background: ASGR2 is a cell surface receptor that binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.
Alias Symbols: HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2
Protein Interaction Partner: MROH5, CERS2, HES1, GLUD1, VKORC1, Sec61b, ERLEC1, OS9, SYVN1, DERL1, FBXO6, EDEM1, F8, ASGR2, ASGR1,
Protein Size: 311

Molecular Weight: 34 kDa

Gene ID: 433

NCBI Accession: NM_001181, NP_001172

UniProt: P07307

Pathways: Thyroid Hormone Synthesis