Aspartate beta Hydroxylase antibody (Middle Region)

Catalog No. ABIN2778321

Product Details anti-Aspartate beta Hydroxylase Antibody

Target: Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aspartate beta Hydroxylase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PVEDSQVIVE EVSIFPVEEQ QEVPPETNRK TDDPEQKAKV KKKKPKLLNK

Predicted Reactivity: Dog: 86%, Horse: 93%, Human: 100%, Pig: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ASPH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASPH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 758 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Aspartate beta Hydroxylase

Target: Aspartate beta Hydroxylase (ASPH) (Aspartate beta-Hydroxylase (ASPH))

Alternative Name: ASPH (ASPH Products)

Synonyms: AAH antibody, BAH antibody, CASQ2BP1 antibody, HAAH antibody, JCTN antibody, junctin antibody, 2310005F16Rik antibody, 3110001L23Rik antibody, AI848629 antibody, AW261690 antibody, AW561901 antibody, C79816 antibody, cI-37 antibody, aah antibody, bah antibody, jctn antibody, MGC107896 antibody, cb971 antibody, fb69e10 antibody, fc06d04 antibody, fc95a08 antibody, wu:fb69e10 antibody, wu:fc06d04 antibody, wu:fc95a08 antibody, aspartate beta-hydroxylase antibody, aspartate-beta-hydroxylase antibody, aspartate beta-hydroxylase L homeolog antibody, ASPH antibody, Asph antibody, asph antibody, asph.L antibody

Background: ASPH is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.
Alias Symbols: BAH, CASQ2BP1, HAAH, JCTN, junctin, AAH
Protein Interaction Partner: ASNA1, TARDBP, IQCB1, UBC, NOS2, Htt, APP, CUL3, SQSTM1, TRDN,
Protein Size: 758

Molecular Weight: 86 kDa

Gene ID: 444

NCBI Accession: NM_004318, NP_004309

UniProt: Q12797

Pathways: Positive Regulation of Endopeptidase Activity