TRA2B antibody (N-Term)

Catalog No. ABIN2778898

Product Details anti-TRA2B Antibody

Target: TRA2B (Transformer 2 beta Homolog (TRA2B))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRA2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MSDSGEQNYG ERESRSASRS GSAHGSGKSA RHTPARSRSK EDSRRSRSKS

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SFRS10. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SFRS10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 288 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TRA2B antibody (ABIN2778898)

Fu, Mende, Bhetwal, Baker, Perrino, Wirth, Fisher: "Tra2? protein is required for tissue-specific splicing of a smooth muscle myosin phosphatase targeting subunit alternative exon." in: The Journal of biological chemistry, Vol. 287, Issue 20, pp. 16575-85, (2012) (PubMed).

Target Details for TRA2B

Target: TRA2B (Transformer 2 beta Homolog (TRA2B))

Alternative Name: SFRS10 (TRA2B Products)

Synonyms: sfrs10 antibody, SFRS10 antibody, Htra2-beta antibody, SRFS10 antibody, TRA2-BETA antibody, TRAN2B antibody, 5730405G21Rik antibody, D16Ertd266e antibody, SIG-41 antibody, Sfrs10 antibody, Silg41 antibody, TRA2beta antibody, Srsf10 antibody, zgc:56612 antibody, transformer 2 beta homolog (Drosophila) antibody, transformer 2 beta homolog L homeolog antibody, transformer 2 beta homolog antibody, tra2b antibody, tra2b.L antibody, TRA2B antibody, Tra2b antibody

Background: SFRS10 contains 1 RRM (RNA recognition motif) domain and belongs to the splicing factor SR family. It is a sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.
Alias Symbols: SFRS10, SRFS10, TRAN2B, TRA2-BETA, Htra2-beta
Protein Interaction Partner: SUMO3, SUMO2, EED, CLK3, SRPK2, SRPK1, YWHAE, HNRNPA1, CDK6, YTHDC1, RBMX, RNPS1, SRSF10, NXF1, UBC, SRSF6, SRSF4, SRSF3, SRSF2, MAGOH, EIF4A3, BARD1, PAXIP1, PPP4R2, SF3B1, FAF2, PSIP1, GCN1L1, EIF4H, SRSF7, SRSF5, SRSF1, S100A9, RBMS2, RAN, PRKDC, NHP2L
Protein Size: 288

Molecular Weight: 32 kDa

Gene ID: 6434

NCBI Accession: NM_004593, NP_004584

UniProt: P62995