LSM4 antibody (Middle Region)

Catalog No. ABIN2779032

Product Details anti-LSM4 Antibody

Target: LSM4 (LSM4 Homolog, U6 Small Nuclear RNA Associated (LSM4))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSM4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GRGGLQQQKQ QKGRGMGGAG RGVFGGRGRG GIPGTGRGQP EKKPGRQAGK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against LSM4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LSM4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 139 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-LSM4 antibody (ABIN2779032)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for LSM4

Target: LSM4 (LSM4 Homolog, U6 Small Nuclear RNA Associated (LSM4))

Alternative Name: LSM4 (LSM4 Products)

Synonyms: GRP antibody, YER112W antibody, LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated S homeolog antibody, LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated antibody, lsm4.S antibody, LSM4 antibody, Lsm4 antibody

Background: Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2, MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2, MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: YER112W, GRP
Protein Interaction Partner: IKZF1, CALCOCO2, PSTPIP1, L3MBTL3, ZBTB10, UBC, WWOX, SMIM14, RHOXF2, LSM8, LSM7, LSM1, COX5B, TOE1, SMU1, SLC22A2, RMI2, PYROXD1, LSM2, VAC14, WDR44, LSM3, LSM5, LSM6, HUWE1, PPIP5K1, PRPF18, DDX39B, TCEA2, SGTA, RAD23A, PPIB, MTR, GTF2B, TOP1, RNU6ATAC,
Protein Size: 139

Molecular Weight: 15 kDa

Gene ID: 25804

NCBI Accession: NM_012321, NP_036453

UniProt: Q9Y4Z0