Double-stranded RNA-binding protein Staufen homolog 2 (STAU2) (C-Term) antibody

Catalog No. ABIN2779060

Product Details

Target: Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Sequence: STNLQDQLEK TGENKGWSGP KPGFPEPTNN TPKGILHLSP DVYQEMEASR

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against STAU2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human STAU2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)

Alternative Name: STAU2 (STAU2 Products)

Synonyms: r-staufen protein antibody, staufen (RNA binding protein) homolog 2 (Drosophila) antibody, staufen double-stranded RNA binding protein 2 antibody, Stau2 antibody

Background: Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5 % and 59.9 % similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: UBC, ZNF346, DICER1, PRKRA, UPF1, EIF2AK2, ADAR, BMI1, COPS5, ELAVL1, DHX58, tat, KIAA1377,
Protein Size: 398

Molecular Weight: 43 kDa

Gene ID: 27067