ID3 antibody (N-Term)

Catalog No. ABIN2779348

Product Details anti-ID3 Antibody

Target: ID3 (Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein (ID3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Horse, Cow, Sheep, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ID3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SPVRGCYEAV CCLSERSLAI ARGRGKGPAA EEPLSLLDDM NHCYSRLREL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against ID3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of ID3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 119 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ID3

Target: ID3 (Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein (ID3))

Alternative Name: ID3 (ID3 Products)

Synonyms: HEIR-1 antibody, bHLHb25 antibody, Hlh462 antibody, Idb3 antibody, fa56g03 antibody, tdsubc_2g3 antibody, wu:fa56g03 antibody, ik:tdsubc_2g3 antibody, xx:tdsubc_2g3 antibody, XId3 antibody, XIdI antibody, XIdIa antibody, XIdIb antibody, XIdx antibody, heir-1 antibody, id3 antibody, xid3 antibody, xidia antibody, ID3 antibody, XIdIIa antibody, inhibitor of DNA binding 3, HLH protein antibody, inhibitor of DNA binding 3 antibody, inhibitor of DNA binding 3, HLH protein L homeolog antibody, inhibitor of DNA binding 3, HLH protein S homeolog antibody, ID3 antibody, Id3 antibody, id3 antibody, id3.L antibody, id3.S antibody

Background: ID3 is a member of the ID family. The members of the family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.
Alias Symbols: HEIR-1, bHLHb25
Protein Interaction Partner: UBC, TCF12, TCF3, TCF4, FAM74A1, ZNF626, ZNF408, RND1, PUF60, ZNF3, MLX, CNOT3, ID3, GNB2, FHL2, CSK, ATF3, CDK2, SMURF2, PRDM14, CBFA2T2, SAP30, IKBKG, E2F4, GATA4, NKX2-5, ID4, GTF2A1L, ELK4, ELK1, SREBF1, PAX5, MYF6, MYF5, MYOG, MYOD1, IFI16, HES1, RUN
Protein Size: 119

Molecular Weight: 13 kDa

Gene ID: 3399

NCBI Accession: NM_002167, NP_002158

UniProt: Q02535