KIN antibody (Middle Region)

Catalog No. ABIN2779549

Product Details anti-KIN Antibody

Target: KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EEKTAKFIEE QVRRGLEGKE QEVPTFTELS RENDEEKVTF NLSKGACSSS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KIN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KIN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 393 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KIN

Target: KIN (KIN, Antigenic Determinant of RecA Protein Homolog (KIN))

Alternative Name: KIN (KIN Products)

Synonyms: Kin17 antibody, BTCD antibody, KIN17 antibody, Kin17 DNA and RNA binding protein antibody, Kin17 DNA and RNA binding protein S homeolog antibody, Kin antibody, kin.S antibody, KIN antibody

Background: Kin is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by the human ortholog.The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog.
Alias Symbols: BTCD, KIN17
Protein Interaction Partner: UBC, HECW2, RPA1, PCNA, METTL22, Bud13, RPA2,
Protein Size: 393

Molecular Weight: 45 kDa

Gene ID: 22944

NCBI Accession: NM_012311, NP_036443

UniProt: O60870