TLE3 antibody (N-Term)

Catalog No. ABIN2779589

Product Details anti-TLE3 Antibody

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GSSSGLLALG ALGSQAHLTV KDEKNHHELD HRERESSANN SVSPSESLRA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against TLE3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TLE3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 772 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TLE3

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Alternative Name: TLE3 (TLE3 Products)

Synonyms: TLE3 antibody, ESG antibody, ESG1 antibody, Xesg1 antibody, esg2 antibody, esg3 antibody, grg2 antibody, grg3 antibody, hst18976 antibody, tle3 antibody, xgrg3 antibody, ESG3 antibody, GRG3 antibody, HsT18976 antibody, Esp3 antibody, 2610103N05Rik antibody, Grg3a antibody, Grg3b antibody, mKIAA1547 antibody, transducin like enhancer of split 3 antibody, transducin like enhancer of split 2 antibody, transducin-like enhancer of split 3 antibody, TLE3 antibody, tle2 antibody, Tle3 antibody

Background: The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.
Alias Symbols: ESG, ESG3, GRG3, HsT18976
Protein Interaction Partner: UBC, COPG1, COPZ1, TBC1D4, PIN1, KLC1, COPB1, ARCN1, NLK, UBD, SRXN1, SEC24A, AHCYL1, SSSCA1, ALYREF, UBA2, S100A9, PPM1G, IGBP1, APP, HINFP, tcf7l1a, lnx2b, NDRG1, CUL4B, SIX3, FOXG1, AES, SIX4,
Protein Size: 772

Molecular Weight: 83 kDa

Gene ID: 7090

NCBI Accession: NM_005078, NP_005069

UniProt: Q04726

Pathways: SARS-CoV-2 Protein Interactome