NFKBIE antibody (Middle Region)
Quick Overview for NFKBIE antibody (Middle Region) (ABIN2780607)
Target
See all NFKBIE AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- DARMLNGCTP LHLAAGRGLM GISSTLCKAG ADSLLRNVED ETPQDLTEES
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Predicted Reactivity
- Cow: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 92%
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Characteristics
- This is a rabbit polyclonal antibody against NFKBIE. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human NFKBIE
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 500 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NFKBIE (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE))
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Alternative Name
- NFKBIE
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Background
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NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NF-ka
Alias Symbols: IKBE
Protein Interaction Partner: UBC, KBTBD7, ANKHD1, RELA, C1QBP, LOC440434, HDAC5, HDAC4, NCOR2, CUL1, SKP1, PPP6C, JUP, REL, NFKB2, NFKB1, IL1A,
Protein Size: 500 -
Molecular Weight
- 53 kDa
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Gene ID
- 4794
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NCBI Accession
- NM_004556, NP_004547
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UniProt
- O00221
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Pathways
- NF-kappaB Signaling, Maintenance of Protein Location
Target
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