TAF6 antibody (C-Term)

Catalog No. ABIN2780702

Product Details anti-TAF6 Antibody

Target: TAF6 (TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Guinea Pig, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF6 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Sequence: PSVQPIVKLV STATTAPPST APSGPGSVQK YIVVSLPPTG EGKGGPTSHP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against TAF6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TAF6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 677 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TAF6

Target: TAF6 (TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6))

Alternative Name: TAF6 (TAF6 Products)

Synonyms: CG32211 antibody, CG9348 antibody, Dmel\\CG32211 antibody, SR3-4B antibody, TAF antibody, TAF6 antibody, TAF60 antibody, TAF60/62 antibody, TAFII60 antibody, TAFII60(62) antibody, TAFII62 antibody, TAF[[II]] antibody, TAF[[II]]60 antibody, TAF[[II]]60/62 antibody, TAF[[II]]62 antibody, TFIID antibody, TFIID 62 antibody, Taf-6 antibody, Taf60 antibody, Taf62 antibody, Taf[[II]]60 antibody, d60 antibody, dTAF6 antibody, dTAF62 antibody, dTAFII62 antibody, dTAF[[II]]262 antibody, dTAF[[II]]60 antibody, dTAF[[II]]62 antibody, dmTAF6 antibody, dme-TAFII60 antibody, l(3)76BDf antibody, p62 antibody, taf6 antibody, taf60 antibody, wu:fb83e08 antibody, wu:fj30b02 antibody, zgc:92160 antibody, 80kDa antibody, AW549759 antibody, TAF(II)80 antibody, TAFII70 antibody, Taf2e antibody, p80 antibody, TAF(II)60 antibody, MGC:8964 antibody, TAF(II)70 antibody, TAF2E antibody, TAFII-70 antibody, TAFII-80 antibody, TAFII80 antibody, TAFII85 antibody, TBP-associated factor 6 antibody, TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor antibody, TATA-box binding protein associated factor 6 antibody, TATA-box binding protein associated factor 6 L homeolog antibody, Taf6 antibody, taf6 antibody, taf6.L antibody, TAF6 antibody

Background: TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF6 is one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1,the largest subunit of TFIID. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Four isoforms have been identified but complete transcripts have been determined for only three isoforms. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.
Alias Symbols: DKFZp781E21155, MGC:8964, TAF2E, TAFII70, TAFII80, TAFII85, TAFII-70, TAFII-80, TAF(II)70, TAF(II)80
Protein Interaction Partner: SOX5, HNF4A, MED26, TRRAP, HIST3H3, UBC, TBP, AHR, APP, TAF1L, TAF3, TAF9B, TAF10, TAF9, TAF7, TAF5, TAF4, TAF2, TAF1, KMT2A, USF1, ERCC1, TAF8, KAT2A, SETD7, NR1D2, NCOR1, NFYC, NFYB, NFYA, MBD3, SIN3A, ALL1, SAP30, SMARCC2, SMARCC1, SMARCB1, SMARCA2, RB
Protein Size: 677

Molecular Weight: 73 kDa

Gene ID: 6878

NCBI Accession: NM_005641, NP_005632

UniProt: P49848