ZFP36L2 antibody (N-Term)

Catalog No. ABIN2780810

Product Details anti-ZFP36L2 Antibody

Target: ZFP36L2 (Zinc Finger Protein 36, C3H Type-Like 2 (ZFP36L2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFP36L2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSTTLLSAFY DVDFLCKTEK SLANLNLNNM LDKKAVGTPV AAAPSSGFAP

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ZFP36L2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZFP36L2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 494 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ZFP36L2 antibody (ABIN2780810)

Hudson, Martinez-Yamout, Dyson, Wright: "Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d." in: Nature structural & molecular biology, Vol. 11, Issue 3, pp. 257-64, (2004) (PubMed).

Target Details for ZFP36L2

Target: ZFP36L2 (Zinc Finger Protein 36, C3H Type-Like 2 (ZFP36L2))

Alternative Name: ZFP36L2 (ZFP36L2 Products)

Synonyms: BRF2 antibody, ERF-2 antibody, ERF2 antibody, RNF162C antibody, TIS11D antibody, Brf2 antibody, Tis11d antibody, fi22c11 antibody, wu:fi22c11 antibody, zgc:76924 antibody, ZFP36L2 antibody, XC3H-3 antibody, XC3H-3b antibody, c3h-3 antibody, zfp36l2 antibody, brf2 antibody, erf-2 antibody, erf2 antibody, rnf162c antibody, tis11d antibody, cb198 antibody, cb480 antibody, fk89d11 antibody, id:ibd1247 antibody, sb:cb198 antibody, sb:cb480 antibody, wu:fb80h11 antibody, wu:fb92f07 antibody, wu:fk89d11 antibody, zfp36l1 antibody, zgc:153979 antibody, XC3H-2 antibody, berg36 antibody, brf1 antibody, c3h-2 antibody, cmg1 antibody, erf-1 antibody, erf1 antibody, rnf162b antibody, tis11b antibody, zfp36l1-a antibody, zfp36l1-b antibody, ZFP36 ring finger protein like 2 antibody, zinc finger protein 36, C3H type-like 2 antibody, ZFP36 ring finger protein-like 2 S homeolog antibody, ZFP36 ring finger protein-like 2 L homeolog antibody, ZFP36 ring finger protein-like 2 antibody, zinc finger protein 36, C3H type-like 1a antibody, ZFP36 ring finger protein-like 1 L homeolog antibody, ZFP36L2 antibody, Zfp36l2 antibody, zfp36l2 antibody, zfp36l2.S antibody, zfp36l2.L antibody, zfp36l1a antibody, zfp36l1.L antibody

Background: ZFP36L2 is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.
Alias Symbols: BRF2, ERF2, ERF-2, TIS11D, RNF162C
Protein Interaction Partner: YWHAB, YWHAE, UBC, CUL3,
Protein Size: 494

Molecular Weight: 51 kDa

Gene ID: 678

NCBI Accession: NM_006887, NP_008818

UniProt: Q53TB4

Pathways: Stem Cell Maintenance