NR2E3 antibody (C-Term)

Catalog No. ABIN2780916

Product Details anti-NR2E3 Antibody

Target: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR2E3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EHVEALQDQS QVMLSQHSKA HHPSQPVRFG KLLLLLPSLR FITAERIELL

Predicted Reactivity: Cow: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NR2E3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human NR2E3

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NR2E3

Target: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Alternative Name: NR2E3 (NR2E3 Products)

Synonyms: ESCS antibody, PNR antibody, RNR antibody, RP37 antibody, rd7 antibody, LOC100228348 antibody, A930035N01Rik antibody, wu:fj55b07 antibody, zgc:103631 antibody, nuclear receptor subfamily 2 group E member 3 antibody, nuclear receptor subfamily 2, group E, member 3 antibody, NR2E3 antibody, Nr2e3 antibody, nr2e3 antibody

Background: This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: PNR, RNR, rd7, ESCS, RP37
Protein Size: 322

Molecular Weight: 35 kDa

Gene ID: 10002

NCBI Accession: XM_011521146, XP_011519448

UniProt: Q8IVZ9

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway