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NSMCE1 antibody (Middle Region)

NSMCE1 Reactivity: Human, Rat, Mouse, Guinea Pig, Rabbit, Cow, Goat, Dog, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781252
  • Target See all NSMCE1 Antibodies
    NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))
    Binding Specificity
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 25
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Mouse, Guinea Pig, Rabbit, Cow, Goat, Dog, Horse
    Host
    • 24
    • 1
    Rabbit
    Clonality
    • 25
    Polyclonal
    Conjugate
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    This NSMCE1 antibody is un-conjugated
    Application
    • 24
    • 14
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    KKEAEQVLQK FVQNKWLIEK EGEFTLHGRA ILEMEQYIRE TYPDAVKICN
    Predicted Reactivity
    Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against NSMCE1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human NSMCE1
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 266 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NSMCE1 (Non-SMC Element 1 Homolog (NSMCE1))
    Alternative Name
    NSMCE1 (NSMCE1 Products)
    Synonyms
    zgc:92777 antibody, NSMCE1 antibody, NSE1 antibody, 2510027N19Rik antibody, RGD1307760 antibody, NSE1 homolog, SMC5-SMC6 complex component antibody, NSE1 homolog, SMC5-SMC6 complex component L homeolog antibody, nsmce1 antibody, NSMCE1 antibody, nsmce1.L antibody, Nsmce1 antibody
    Background
    NSMCE1 is a probable component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
    Alias Symbols: NSE1
    Protein Interaction Partner: UBC, EID3, SMC6, NDNL2, Ube2k, UBE2D2, NSMCE2, NSMCE1, NSMCE4A, SMC5, SUMO2, MAGEF1,
    Protein Size: 266
    Molecular Weight
    31 kDa
    Gene ID
    197370
    NCBI Accession
    NM_145080, NP_659547
    UniProt
    Q8WV22
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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