PTPRH antibody (Middle Region)

Catalog No. ABIN2781303

Product Details anti-PTPRH Antibody

Target: PTPRH (Protein tyrosine Phosphatase, Receptor Type, H (PTPRH))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRH antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QTKNSVMLWW KAPGDPHSQL YVYWVQWASK GHPRRGQDPQ ANWVNQTSRT

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PTPRH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PTPRH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1115 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTPRH

Target: PTPRH (Protein tyrosine Phosphatase, Receptor Type, H (PTPRH))

Alternative Name: PTPRH (PTPRH Products)

Synonyms: SAP-1 antibody, si:dkey-197c15.5 antibody, SAP1 antibody, sap-1 antibody, Bem2 antibody, protein tyrosine phosphatase, receptor type, h antibody, protein tyrosine phosphatase, receptor type H antibody, protein tyrosine phosphatase, receptor type, H antibody, ptprh antibody, PTPRH antibody, Ptprh antibody

Background: PTPRH is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. It was also found to be expressed in several cancer cell lines, but not in the corresponding normal tissues.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver, and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines, but not in the corresponding normal tissues.
Alias Symbols: FLJ39938, MGC133058, MGC133059, SAP-1, SAP1
Protein Interaction Partner: KRTAP10-3, KRTAP10-8, DHPS, MLH1, GHR, BCAR1, DOK1, PXN, PTK2, MAPK1, LCK,
Protein Size: 1115

Molecular Weight: 120 kDa

Gene ID: 5794

NCBI Accession: NM_002842, NP_002833

UniProt: Q9HD43