SLC11A2 antibody (N-Term)

Catalog No. ABIN2781546

Product Details anti-SLC11A2 Antibody

Target: SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))

Binding Specificity: N-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC11A2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VLGPEQKMSD DSVSGDHGES ASLGNINPAY SNPSLSQSPG DSEEYFATYF

Specificity: Specific to all four isoforms of the SLC11A2 transporter.

Predicted Reactivity: Human: 100%, Rat: 91%

Characteristics: This is a rabbit polyclonal antibody against SLC11A2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC11A2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 561 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC11A2

Target: SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))

Alternative Name: SLC11A2 (SLC11A2 Products)

Synonyms: DCT1 antibody, DMT1 antibody, NRAMP2 antibody, Nramp2 antibody, mk antibody, van antibody, Dmt1 antibody, ATNRAMP2 antibody, F8G22.4 antibody, F8G22_4 antibody, NRAMP metal ion transporter 2 antibody, dct1 antibody, dmt1 antibody, nramp2 antibody, SLC11A2 antibody, cb426 antibody, fa07b10 antibody, wu:fa07b10 antibody, zgc:136699 antibody, solute carrier family 11 member 2 antibody, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 antibody, NRAMP metal ion transporter 2 antibody, manganese transport protein antibody, metal transporter Nramp2 antibody, solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 antibody, SLC11A2 antibody, Slc11a2 antibody, NRAMP2 antibody, LOC9327403 antibody, slc11a2 antibody

Background: The SLC11A2 is a divalent metal transporter (DMT1), which carries iron, manganese, cobalt, nickel, cadmium, lead, copper, and zinc. DMT1 participates in cellular iron absorption at the luminal surface of the duodenum as well as in other areas of the body.The SLC11A2 gene encodes a divalent metal transporter (DMT1), which carries iron, manganese, cobalt, nickel, cadmium, lead, copper, and zinc. DMT1 participates in cellular iron absorption at the luminal surface of the duodenum as well as in other areas of the body (Hubert and Hentze, 2002 [PubMed 12209011], Ludwiczek et al., 2007 [PubMed 17293870]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DCT1, DMT1, FLJ37416, NRAMP2
Protein Interaction Partner: NDFIP1, UBC, NEDD4, PARK2, NDFIP2,
Protein Size: 561

Molecular Weight: 61 kDa

Gene ID: 4891

NCBI Accession: NM_000617, NP_000608

UniProt: P49281

Pathways: Transition Metal Ion Homeostasis, Proton Transport, Positive Regulation of Endopeptidase Activity